Pharmacologic treatments for covid-19 patients

Analyses are updated every Friday

Methods

Treatment comparisons

Create and download your forest plots with the most up-to-date data here Forest plots

Access the forest plots for the 283 treatment comparisons .

General characteristics of primary studies

Page: 1 / Sorted by: Most recent ↓
Trial Funding Comparisons Design Participants Sample size Overall risk
of bias
Highest assessment
Full description
Treatment 1 Treatment 2
N/A
Dengiz E, Med Gas Res (2021)
Full text
Commentary
Private

Oxygen-Ozone

Standard care

RCT Patients with confirmed COVID-19 (symptomatic, unclear severity) admitted to a single center in Turkey. N=30
Some concerns
Details

Full description

NCT04221737
Ibarra-Estrada MA, Crit Care Med (2021)
Full text
Commentary
Not reported/unclear

APR ventilation

LTV ventilation

RCT Patients with confirmed COVID-19 (critical) admitted to a single center in Mexico. N=101
Some concerns
Details

Full description

NCT04426695
Somersan-Karakaya S, medRxiv (2021)
Full text
Commentary
Commentary
Mixed

REGN-COV2 2400mg

REGN-COV2 800mg

Placebo

RCT Patients with confirmed COVID-19 (mild-moderate) admitted to 103 centers in USA, Brazil, Chile, Mexico, Moldova, and Romania N=1364
Some concerns
Details

Full description

NCT04435795
CONTAIN
Ezer N, BMJ (2021)
Full text
Commentary
Commentary
Mixed

Ciclesonide

Placebo

RCT Outpatients with confirmed COVID-19 (mild, symptomatic) treated by multiple centers in Canada N=215
Some concerns
Details

Full description

CTRI/2020/09/027903
Parikh D, medRxiv (2021)
Full text
Commentary
Commentary
Private

C-IVIG

Standard care

RCT Patients with confirmed COVID-19 (moderate-severe) admitted to 7 centers in India. N=60
Some concerns
Details

Full description

NCT04581811
Page DB, Ann Am Thorac Soc (2021)
Full text
Commentary
No specific funding

Prolonged Proning

Prone position

RCT Patients with confirmed COVID-19 (critical) admitted to a single center in USA N=52
Some concerns
Details

Full description

NCT04427501
Dougan M, Clin Infect Dis (2021)
Full text
Commentary
Commentary
Private

LY-CoV555+LY-CoV016

Placebo

RCT Outpatients with confirmed COVID-19 (mild) treated at multiple centers in the USA and Puerto Rico. N=782
Low
Details

Full description

IRCT20210614051574N5
Haghighi S, SSRN (2021)
Full text
Commentary
Mixed

Thalidomide

Standard care

RCT Patients with confirmed COVID-19 (moderate-severe) admitted to a single center in Iran. N=50
Some concerns
Details

Full description

NCT04330638; EudraCT2020-001500-41
COV-AID
Declercq J, Lancet Respir Med (2021)
Full text
Commentary
Commentary
(21)00405-7
Public/non profit

ANA

Tocilizumab

Siltuximab

ANA

ANA

Tocilizumab

Anakinra + Tocilizumab

Standard care

Standard care

Standard care

Tocilizumab

Siltuximab

Siltuximab

Standard care

RCT Patients with confirmed COVID-19 (moderate-critical) admitted to 16 centers in Belgium. N=342
Some concerns
Details

Full description

NCT04604327
Marcos M, Thromb Haemost (2021)
Full text
Commentary
Commentary
Mixed

Therap AC

Prophylactic AC

RCT Patients with suspected or confirmed COVID-19 (mild-moderate) admitted to 5 centers in Spain. N=0
High
Details

Full description