Who we are What we do Who is using our data Steering committee Operating team Trialists Former contributors Publications Data sharing Monthly updates
Living mapping vaccines
LE synthesis Vaccine RCTs
Vaccine OS
Mapping Treatments tested Pharmacologic treatments Nonpharmacologic treatments Preventive treatments
☰

logo

The COVID-NMA initiative
A living mapping and living systematic review of Covid-19 trials

COVID-NMA is an international research initiative supported by the WHO and Cochrane.

We provide a living mapping of COVID-19 trials. We are also conducting living evidence synthesis on vaccines, preventive interventions and treatments for COVID-19 to assist decision makers.

For 2023, COVID-NMA revised its protocol and reduced its scope.

  • For the living mapping, we continue to update and include all COVID-19 vaccine trials only.
  • For the living evidence synthesis, we continue to update only COVID-19 vaccines boosters.

See the description of our model here and our living review protocol here.

LIVING MAPPING OF TRIALS

(i.e., trials registered on Clinicaltrials.gov and EU clinical trials registries
Updated monthly

4634
Randomized Trials
906 RCTs recruiting

756
RCTs on vaccines
(162 recruiting)
Updated on a monthly basis

382
RCTs on prevention
(59 recruiting)
Last search date 26-01-2023

3496
RCTs on treatments
(685 recruiting)
Last search date 26-01-2023

LIVING SYNTHESIS OF PUBLISHED STUDIES

((include both journals published and preprints)
Updated daily

907
Studies (RCTs or Observational studies) with complete data extraction and results
included in our evidence synthesis

220
RCTs on vaccines
Updated on a monthly basis only for boosters

575
RCTs on treatments
Last search date 14-12-2022

17
RCTs on prevention
Last search date 28-10-2021

95
OS on vaccines
Last search date 04-11-2021

MONTHLY UPDATE

Latest news:
  • Living mapping: Last update August 2, 2023. The review is completed and no further update is planned.
  • Living systematic review Vaccine boosters: Last search date July 30, 2023. No further screening is planned after this date. Extraction is ongoing for all pending studies.

    • August 01, 2023 to August 31, 2023. See the update here.

    Newsletter

    To receive updates on our project, please subscribe below.

    Excluded Studies

    Download CSV file (last update: 2023-04-21).

    Retracted Studies

    Download CSV file (last update: 2022-09-15).

    This work received some funding from the Agence Nationale de la Recherche (ANR), the World Health Organization (WHO), Cochrane France, Center of Research in Epidemiology and StatisticS (CRESS), Centre d’Epidémiologie Clinique (GHU Cochin, Hôtel Dieu), the French Ministry of Higher Education and Research, the French Ministry of Health, Assistance Publique Hôpitaux de Paris (APHP), Université de Paris Cité, Centre national de la recherche scientifique (CNRS), the Federal Ministry of Education and Research (Germany), and VACCELERATE project (funded by the European Union's Horizon 2020 Research and Innovation Programme under agreement No. 101037867).