Pharmacologic treatments for covid-19 patients

Methods

Protocol

Protocol amendment:

As of March 1, 2022, the COVID-NMA revised its protocol to include only studies evaluating immunomodulators and antiviral therapies. Comparisons evaluating antivirals and immunomodulators will continue to be updated every two weeks.

For treatments that are neither immunomodulators nor antivirals, we provide the updated results up to Feb 28, 2022 including all identified reports through our search strategy up tp this date.

meta-COVID

Perform your own analysis using COVID-NMA data, create and download your forest plots by clicking below:

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Treatment comparisons

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Your research: Proxalutamide

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General characteristics of primary studies

Trial Funding Comparisons Design Participants Sample size Overall risk
of bias
Highest assessment
Full description
Treatment 1 Treatment 2
NCT04728802
Cadegiani F, medRxiv, 2021
Full text
Commentary
Commentary
Private

Proxalutamide

Placebo

RCT Patients with confirmed COVID-19 (mild-severe) admitted to 8 centers in Brazil. N=645
Low
Details

Full description

NCT04446429
Cadegiani FA, Cureus, 2021
Full text
Commentary
Commentary
Mixed

Proxalutamide

Placebo

RCT Male outpatients with confirmed COVID-19 (mild) treated at 2 centers in Brazil. N=262
High
Details

Full description