COVID-19 vaccine effectiveness
(Randomized evidence)

If you want to see all comparisons, please click here

ModernaTX - mRNA-1273 vs Placebo

Forest plots were updated on January 19th, 2021.
The Evidence profile and Summary of Findings table were updated on January 25th, 2021.

You will find below the forest plots for this comparison with the general characteristics and risk of bias assessment for all RCTs identified.
Of note all trials may not be included in the synthesis.

Forest plots
(last update: 2021-01-18)

Trial subgroup analysis
(last update: 2021-01-18)

Evidence profile
2021-01-27

Summary of findings
2021-01-27

Trial Type Comparisons Design Participants Sample size Overall risk
of bias
Highest assessment
Full description
Intervention 1 Intervention 2
NCT04470427
ModernaTX
Baden LR, N Engl J Med, 2020
COVE

Full text
Commentary
RNA based vaccine

mRNA-1273

Placebo

RCT
Phase 3
Healthy adults with no known history of SARS-CoV-2 infection in 99 centers in the US N=30420
Some concerns
Details

Full description