Weekly Update

Weekly update: October 12, 2020 to October 16, 2020

We identified and now report nine new RCTs on our website comparisons:

  • Rajasingham et al, Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers,
  • Abella et al, Efficacy and Safety of Hydroxychloroquine vs Placebo for Pre-exposure SARS-CoV-2 Prophylaxis Among Health Care Workers A Randomized Clinical Trial,
  • Balcells et al, Early Anti-SARS-CoV-2 Convalescent Plasma in Patients Admitted for COVID-19: A Randomized Phase II Clinical Trial,
  • Zhao et al, Tocilizumab combined with favipiravir in the treatment of COVID-19: A multicenter trial in a small sample size ,
  • Lemos et al, Therapeutic versus prophylactic anticoagulation for severe COVID-19: A randomized phase II clinical trial (HESACOVID),
  • Wu et al, Efficacy and safety of triazavirin therapy for coronavirus disease 2019: A pilot randomized controlled trial,
  • Fu et al, evluating the combination of IFN-κ plus TFF2 with standard care in the treatment of patients with moderate COVID-19,
  • Dabbous et al, Comparing the applicability of shared room and single room occupancy ,
  • Ansarin et al, Effect of bromhexine on clinical outcomes and mortality in COVID-19 patients: A randomized clinical trial .

    The following studies are updated based on the latest published papers:

  • Beigel et al, evaluating Remdesivir
  • RECOVERY Horby et al , evaluating hydroxychloroquine

    We have also included and presently extracting the following new RCTs:

  • SOLIDARITY, Repurposed antiviral drugs for COVID-19; interim WHO SOLIDARITY trial results,
  • Altay et al, Combined metabolic cofactor supplementation accelerates recovery in mild-to-moderate COVID-19,

    In addition to a new vaccine study:

  • Pu et al, An in-depth investigation of the safety and immunogenicity of an inactivated SARS-CoV-2 vaccine.

    Some RCTs were extracted and pending awaiting author’s reply due to missing outcome data.

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