Pending pharmacological RCTs

As of December 14, 2022, the COVID-NMA revised its protocol and stopped including pharmacological interventions trials. List of studies included but not extracted here

Arends EJ,J. Am. Soc. Nephrol, 2022 Antiviral Effects of Voclosporin on SARS-CoV-2 in Immunocompromised Kidney Patients
Cafardi J, JAMA Netw Open, 2022 Efficacy and Safety of Pacritinib vs Placebo for Patients With Severe COVID-19: A Phase 2 Randomized Clinical Trial.
Corral-Gudino L, Eur J Clin Invest, 2022 Effect of intravenous pulses of methylprednisolone 250 mg versus dexamethasone 6 mg in hospitalized adults with severe COVID-19 pneumonia: an open-label randomized trial
Denkinger C M, medrxiv, 2022 Anti-SARS-CoV-2 antibody containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19 via increased neutralizing antibody activity. A randomized clinical trial
Hepprich M, EClinicalMedicine, 2022 Canakinumab in patients with COVID-19 and type 2 diabetes - A multicentre, randomised, double-blind, placebo-controlled trial
Ilaria Mastrorosa I, SSRN, 2022 Sarilumab Plus Standard of Care Versus Standard of Care for the Treatment of Severe COVID-19: A Phase 3, Randomized, Open-Labeled, Multi-Center Study (ESCAPE Study)
Jalili E, Tanaffos, 2022 (PRESECO) Effect of Convalescent Plasma Therapy on Clinical Improvement of COVID-19 Patients: a Randomized Clinical Trial
Ko ER, medrxiv, 2022 Abatacept for Treatment of Adults Hospitalized with Moderate or Severe Covid-19
Mastrorosa I, Top. antivir. Med, 2022 SARILUMAB PLUS STANDARD of CARE (SOC) VERSUS SOC for SEVERE COVID-19 (ESCAPE STUDY)
McMahon JH, EClinicalMedicine, 2022 Favipiravir in early symptomatic COVID-19, a randomised placebo-controlled trial
Muller-Tidow C, Hemasphere, 2022 A RANDOMIZED CONTROLLED CLINICAL TRIAL DEMONSTRATES THAT PLASMA FROM CONVALESCENT AND VACCINATED DONORS IMPROVES OUTCOME OF COVID-19 IN PATIENTS WITH HEMATOLOGICAL DISEASE, CANCER OR IMMUNOSUPPRESSION
NCT04448756 M5049 Study in Participants With Coronavirus Disease 2019 (COVID-19) Pneumonia
NCT04472494 Study of Abatacept in the Treatment of Hospitalized COVID-19 Participants With Respiratory Compromise
NCT04480424 Study to Evaluate the Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) Plus Standard Medical Treatment (SMT) Versus SMT Alone in Participants in Intensive Care Unit (ICU) With Coronavirus Disease (COVID-19)
O'Halloran J, medrxiv, 2022 Infliximab for Treatment of Adults Hospitalized with Moderate or Severe Covid-19
Rein L, Crit Care Med, 2022 Randomized Phase 3 Trial of Ruxolitinib for COVID-19-Associated Acute Respiratory Distress Syndrome
Salton F, Eur Respir J, 2022 Prolonged higher dose methylprednisolone vs. conventional dexamethasone in COVID-19 pneumonia: a randomised controlled trial (MEDEAS).
Terada J, Drug Discov Ther, 2022 Impact of inhaled ciclesonide on asymptomatic or mild COVID-19: a randomized trial
Thorlacius-Ussing L, Sci Rep, 2022 A randomized placebo-controlled trial of convalescent plasma for adults hospitalized with COVID-19 pneumonia.
Ullah S, Medicina (Kaunas), 2022 Assessment of Tocilizumab (Humanized Monoclonal Antibody) for Therapeutic Efficacy and Clinical Safety in Patients with Coronavirus Disease (COVID-19)
Villanueva C, medrxiv, 2022 Efficacy and safety of convalescent plasma versus standard care in hospitalized patients with COVID-19 from the Peruvian Social Security Health System: open-label, randomized, controlled clinical trial
Wu H, PloS one, 2022 Low-dose versus high-dose dexamethasone for hospitalized patients with COVID-19 pneumonia: a randomized clinical trial