Pharmacologic treatments for covid-19 patients

Hydroxychloroquine + Azithromycin vs Hydroxychloroquine

This comparison will not be updated. Last search date 28 Feb, 2022.


Outpatients

Forest plots
(last update: 2022-04-12)

Summary of findings
(last update: 2022-05-04)

Hospitalized patients

Forest plots
(last update: 2022-04-12)

Summary of findings
(last update: 2022-05-04)

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Permanent URL for this comparison: https://covid-nma.com/living_data/index.php?comparison=29

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Trial Funding Comparisons Design Participants Sample size Overall risk
of bias
Highest assessment
Full description
Treatment 1 Treatment 2
NCT04354428
Johnston C, EClinicalMedicine, 2021
Full text
Commentary
Commentary
Commentary
Public/non profit

HCQ+AZM

HCQ+Placebo

HCQ+AZM

Vitamin C+Placebo

Vitamin C+Placebo

HCQ+Placebo

RCT Outpatients with confirmed COVID-19 (asymptomatic-mild) treated by 5 centers in the USA N=231
Some concerns
Details

Full description

NCT04349592
Q-PROTECT
Omrani A, EClinicalMedicine, 2020
Full text
Commentary
Public/non profit

HCQ+AZM

Hydroxychloroquine

HCQ+AZM

Placebo

Placebo

Hydroxychloroquine

RCT Outpatients with confirmed COVID-19 (mild) treated by 2 centers in Qatar N=456
Some concerns
Details

Full description

NCT04321278
Furtado RHM, Lancet, 2020
Full text
Mixed

HCQ+AZM

Hydroxychloroquine

RCT Patients with suspected or confirmed COVID-19 (moderate-critical) admitted to 57 centers in Brazil N=447
Some concerns
Details

Full description

NCT04322123
Cavalcanti AB, N Engl J Med, 2020
Full text
Commentary
Mixed

HCQ+AZM

Hydroxychloroquine

Hydroxychloroquine

Standard care

RCT Patients with suspected or confirmed COVID-19 (mild-moderate) admitted to 55 centers in Brazil N=667
Some concerns
Details

Full description