Pharmacologic treatments for covid-19 patients

Casirivimab+Imdevimab (REGN-COV2) vs Standard care/Placebo


Outpatients

Forest plots
(last update: 2022-04-29)

Summary of findings
(last update: 2022-03-29)

Hospitalized patients

Forest plots
(last update: 2022-05-16)

Summary of findings
(last update: 2022-05-16)

To access all information :

You can print it as a pdf. You can also click on each forest plot with your right mouse button and download.

Permanent URL for this comparison: https://covid-nma.com/living_data/index.php?comparison=192

Back to your research

Trial Funding Comparisons Design Participants Sample size Overall risk
of bias
Highest assessment
Full description
Treatment 1 Treatment 2
NCT04426695
Somersan-Karakaya S, medRxiv, 2022
Full text
Full text
Commentary
Commentary
Mixed

REGN-COV2 2.4g

REGN-COV2

Placebo

RCT Patients with confirmed COVID-19 (mild-moderate) admitted to 103 centers in USA, Brazil, Chile, Mexico, Moldova, and Romania N=1364
Some concerns
Details

Full description

NCT04452318
O'Brien M, JAMA, 2022
Full text
Full text
Full text
Commentary
Commentary
Commentary
Mixed

REGN-COV2

Placebo

RCT Outpatients with confirmed COVID-19 (asymptomatic) treated at 112 centers in the Moldova, Romania, and USA. N=314
Some concerns
Details

Full description

NCT04381936, EudraCT 2020-001113-21, ISRCTN5018967
RECOVERY-REGEN
Horby P, Lancet, 2022
Full text
Full text
Commentary
Commentary
Commentary
Mixed

REGN-COV2

Standard care

RCT Patients with suspected or confirmed COVID-19 (mild-critical) admitted to 127 centers in the UK N=9785
Some concerns
Details

Full description

NCT04425629
Weinreich D (2), N Engl J Med, 2021
Full text
Full text
Full text
Commentary
Commentary
Commentary
Mixed

REGN-COV2

Placebo

RCT Outpatients with confirmed COVID-19 (mild) treated at 82 centers in Mexico and the USA. N=1678
Some concerns
Details

Full description

NCT04425629
Weinreich DM, N Engl J Med, 2020
Full text
Commentary
Mixed

REGN-COV2

Placebo

RCT Outpatients with COVID-19 (symtomatic-mild) treated at 27 centers in USA N=275
Low
Details

Full description