Vaccines for covid-19 patients

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Gam-COVID-Vac rAd26-S/rAd5-S vs Placebo

You will find below the forest plots for this comparison with the general characteristics and risk of bias assessment for all RCTs identified.
Of note all trials may not be included in the synthesis.

Forest plots

Evidence profile

Summary of findings

Trial Comparisons Design Participants Sample size Overall risk of bias
Primary outcome
Full description
Treatment 1 Treatment 2
Gamaleya Research Institute of Epidemiology and Microbiology
Logunov D, RESIST, 2021

Full text
Gam-COVID-Vac rAd26-S/rAd5-S Placebo RCT
Phase 3
SARS-CoV-2- and HIV infection-free adult volunteers at 25 centers in Russia N=21977
Some concerns

Full description

The link in the column "Overall risk of bias" provides access to a complete description of the assessment of each risk of bias domain with supports for judgement produced using the Revised Cochrane risk-of-bias tool for randomized trials RoB 2.

The risk of bias by domain as well as overall risk of bias reported in the table corresponds to the highest risk of bias for the outcomes assessed for the systematic review. The link in the column "Full description" provides access to the general characteristics of the study.

We acknowledge that we may have been unable to extract some information from pre-prints, as they represent preliminary forms of scientific communication.