COVID-19 vaccine effectiveness
If you want to see all comparisons, please click here
Gam-COVID-Vac (Sputnik V) vs Placebo
You will find below the forest plots for this comparison with the general characteristics and risk of bias assessment for all RCTs identified.
Of note all trials may not be included in the synthesis.
|Trial||Type||Comparisons||Design||Participants||Sample size||Overall risk
|Intervention 1||Intervention 2|
Gamaleya Research Institute of Epidemiology and Microbiology
Logunov D, Lancet, 2021
|Non replicating viral vector||
GAM-COVID-VAC (SPUTNIK V)
|RCTPhase 3||SARS-CoV-2- and HIV infection-free adult volunteers at 25 centers in Russia||N=21977||
For risk of bias assessment, we are considering the “effect of assignment to intervention” which might not be the analysis planned and reported by investigators. Consequently, when investigators planned to assess and report the “per-protocol” effect, the risk of bias for domain 2 may be evaluated as “some concerns”. We will contact investigators to obtain the results of the intent-to-treat analysis.