COVID-19 vaccine effectiveness
(Randomized evidence)
Search studies
Trial | Type | Comparisons | Design | Participants | Sample size | Overall risk of bias Highest assessment |
Full description | |
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Intervention 1 | Intervention 2 | |||||||
ChiCTR2000034825 ; NCT04523571 BioNTech RNA Pharmaceuticals Li J, Nature Medicine, 2021 Full text Commentary |
RNA based vaccine |
BNT162b1 10 mcg D0/21 BNT162b1 30 mcg D0/21 |
Placebo |
RCTPhase 1 | Healthy young adults between 18 and 55 years of age, and older adults between 65 and 85 that were SARS-COVID-2 infection-free at a single center in China. | N= 144 |
Low Details |