Pharmacologic treatments for covid-19 patients

Umbilical cord mesenchymal stem cell infusion vs Standard care/Placebo

This comparison will not be updated. Last search date 28 Feb, 2022.


Hospitalized patients

Forest plots
(last update: 2022-04-03)

Summary of findings
(last update: 2022-05-03)

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Permanent URL for this comparison: https://covid-nma.com/living_data/index.php?comparison=60

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Trial Funding Comparisons Design Participants Sample size Overall risk
of bias
Highest assessment
Full description
Treatment 1 Treatment 2
NCT04333368, EudraCT 2020-001287-28
Monsel A, Crit Care, 2022
Full text
Commentary
Public/non profit

UC-MSC

Placebo

RCT Patients with confirmed COVID-19 (severe-critical) admitted to 10 centers in France N=47
Low
Details

Full description

NCT04457609
Dilogo IH, Stem Cells Transl Me, 2021
Full text
Commentary
Public/non profit

UC-MSC

Placebo

RCT Patients with confirmed COVID-19 (critical) admitted to a 4 centers in Indonesia N=40 N/A

Full description

NCT04355728
Lanzoni G, Stem Cells Transl Me, 2021
Full text
Full text
Commentary
Commentary
Mixed

UC-MSC

Placebo

RCT Patients with confirmed COVID-19 (severe-critical) admitted to a single center in USA N=24
Some concerns
Details

Full description

NCT04288102
Shi L, eBioMedicine, 2022
Full text
Full text
Full text
Commentary
Public/non profit

hUC-MSC

Placebo

RCT Patients with confirmed COVID-19 (mild-moderate) admitted to two centers in China N=101
Some concerns
Details

Full description

ChiCTR2000031494
Shu L, Stem Cell Res Ther, 2020
Full text
Commentary
Public/non profit

hUC-MSC

Standard care

RCT Patients with COVID-19 (severe) admitted to a single center China N=41
Some concerns
Details

Full description