Pharmacologic treatments for covid-19 patients

Tofacitinib vs Standard care/Placebo

This comparison will not be updated. Last search date 14 Dec, 2022


Hospitalized patients

Forest plots
(last update: 2022-03-04)

Summary of findings
(last update: 2022-09-27)

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Permanent URL for this comparison: https://covid-nma.com/living_data/index.php?comparison=421

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Trial Funding Comparisons Design Participants Sample size Overall risk
of bias
Highest assessment
Full description
Treatment 1 Treatment 2
N/A
Murugesan H , J Assoc Physicians India, 2021
Full text
Private

Tofacitinib

Standard care

RCT Patients with confirmed COVID-19 (moderate-severe) admitted to a single center in India. N=100
Some concerns
Details

Full description

NCT04469114
STOP-COVID
Guimaraes P, N Engl J Med, 2021
Full text
Commentary
Private

Tofacitinib

Placebo

RCT Patients with confirmed COVID-19 (mild-moderate-severe) admitted to 15 centers in Brazil N=289
Low
Details

Full description