Pharmacologic treatments for covid-19 patients

Camostat Mesilate vs Placebo


Outpatients

Forest plots
(last update: 2022-10-20)

Summary of findings
(last update: 2022-10-23)

Hospitalized patients

Forest plots
(last update: 2022-10-20)

Summary of findings
(last update: 2022-10-23)

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Permanent URL for this comparison: https://covid-nma.com/living_data/index.php?comparison=374

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Trial Funding Comparisons Design Participants Sample size Overall risk
of bias
Highest assessment
Full description
Treatment 1 Treatment 2
NCT04524663
COPS-2003
NCT04524663, Unpublished, 2022
Full text
Not reported/unclear

Camostat Mesilate

Placebo

RCT Outpatients with confirmed COVID-19 (mild) treated by one center in the USA. N=49
Some concerns
Details

Full description

NCT04583592
CAMELOT
NCT04583592, Unpublished, 2022
Full text
Not reported/unclear

Camostat Mesilate

Placebo

RCT Outpatients with confirmed COVID-19 (mild) treated by multiple centers in the USA. N=295
Low
Details

Full description

NCT04625114
Tobback E, Int J Infect Dis, 2022
Full text
Commentary
Mixed

Camostat Mesilate

Placebo

RCT Outpatients with confirmed COVID-19 (asymptomatic-mild) treated at a single center in Belgium. N=96
Some concerns
Details

Full description

NCT04657497; jRCT2031200198
CANDLE
Kinoshita T, BMC Medicine, 2022
Full text
Full text
Commentary
Commentary
Commentary
Private

Camostat Mesilate

Placebo

RCT Patients with confirmed COVID-19 (asymptomatic-mild) admitted to 21 centers in Japan. N=155
Some concerns
Details

Full description

NCT04353284
Chupp G, medRxiv, 2022
Full text
Commentary
Commentary
Mixed

Camostat Mesilate

Placebo

RCT Outpatients with confirmed COVID-19 (mild) treated at a single center in USA. N=70
Some concerns
Details

Full description

NCT04321096 ; EudraCT Number: 2020001,20042
Gunst J, EClinicalMedicine, 2021
Full text
Commentary
Private

Camostat Mesilate

Placebo

RCT Patients with confirmed COVID-19 (mild-severe) admitted to 9 centers in Denmark and Sweden. N=208
Some concerns
Details

Full description