Trial NCT04505722
Publication Sadoff J, N Engl J Med, 2021
Primary outcome on the report: Vaccine efficacy against moderate to severe–critical coronavirus disease 2019 (Covid-19) with an onset at least 14 days and at least 28 days after administration among partici-pants in the per-protocol population who had tested negative for SARS-CoV-2. Safety was also assessed.

Note: The risk of bias by domain corresponds to the highest risk of bias among outcomes by domain.
The overall risk of bias corresponds to the overall highest risk of bias assessed among outcomes.