Study registration: *
Publication Murugesan M, SSRN, 2021
Dates: 2021-01-01 to 2021-05-31
Funding: No specific funding (None to declare)
Conflict of interest: no COI (None to declare)

Methods

Study design:Cohort
Description of participants: Health care workers without previous COVID-19 infection at a single center in Vellore, India.
Inclusion criteria:
  • Healthcare worker
  • staff of Christian Medical College, Vellore, India
  • assessed between April 16 to May 30, 2021.

Exclusion criteria:
  • Prior infection with SARS-COV2
  • Students and temporary workers

Follow-up duration (months): 5.03
Vaccines:
  • 2 doses of ChAdOx1-S or BBV152
Variant description :
Variant name: Delta
Evidence: Indirect evidence (prevalence of variant in the population: 1 to 95%)
Documents
available

Protocol

NR

Statistical plan

No

Data-sharing stated: Yes
Data accessibility: Corresponding author Dr Priscilla Rupali MD Email: prisci@cmcvellore.ac.in The de-identified dataset and analysis code is included in the supplementary appendix

General comment Concerns about uncontrolled confounding; factors such as socio-economic status andcommorbidities were not adjusted for.