Study registration: *
Publication Elliott P, medRxiv, 2021
Dates: 2020-12-08 to 2021-07-12
Funding: Public/non profit (Department of Health and Social Care in England. Sequencing was provided through funding from COG-UK)
Conflict of interest: no COI (The authors have declared no competing interest. )

Methods

Study design:Cross-sectional
Description of participants: Adults aged 18 to 64 years In England, UK.
Inclusion criteria:
  • Adults aged 18 to 64 years
  • registered with a general practitioner in England. Non-overlapping random cross-sectional samples of the population in England at ages 5 years and above were sent invitation letters through the post.

Exclusion criteria:
  • *

Follow-up duration (months): 7.0
Vaccines:
  • 1 or 2 doses of BNT162b2 or mRNA-1273 or ChAdOx1
Variant description :
Variant name: Delta
Evidence: Indirect evidence (prevalence of variant in the population: 100)
Documents
available

Protocol

NR

Statistical plan

No

Data-sharing stated: No
Data accessibility: The datasets generated or analysed, or both, during this study are not publicly available because of governance restrictions.
General comment Concerns around failure to adjust for several important confounders and use of self-reported vaccination status, which had a large amount of missing data.