Covid-19 Living Data

Study registration: *
Publication Fowlkes A, MMWR, 2021
Dates: 2020-12-14 to 2021-08-14
Funding: Public/non profit (National Center for Immunization and Respiratory Diseases and the Centers for Disease Control and Prevention (contracts 75D30120R68013 to Marshfield Clinic Research Institute, 75D30120C08379 to the University of Arizona, and 75D30120C08150 to Abt Associates).)
Conflict of interest: no COI (All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. Matthew S. Thiese reports grants and personal fees from Reed Group and the American College of Occupational and Environmental Medicine, outside the submitted work. No other potential conflicts of interest were disclosed.)

Methods
Methods	Study design:Cohort Description of participants: Adults with occupation involving regular direct contact (within three feet) with others, ) Inclusion criteria: The HEROES-RECOVER network includes prospective cohorts from two studies: HEROES (the Arizona Healthcare, Emergency Response, and Other Essential Workers Surveillance Study) and RECOVER (Research on the Epidemiology of SARS-CoV-2 in Essential Response Personnel). 18–85 years who currently work at least 20 hours per week in an occupation involving regular direct contact (within three feet) with others, assessed at the participant level. The occupations are categorized as Health Care Personnel (HCP), First Responders (FR), or Other Essential Workers (OEW). HCP include clinical providers and support staff in inpatient, outpatient, or residential settings. FR include firefighters, emergency medical services, law enforcement, border patrol, and correctional officers. OEW include workers in the following sectors: education, agriculture and food processing, public and other transportation services, solid waste collection, warehouse and delivery, utilities, government and community-based services, childcare, information technology, 6 environmental services, and hospitality. All participants must have access to a smartphone or internet-connected computer, a mailing address, and ability to speak or write English or Spanish. Exclusion criteria: Exclusion criteria include receipt of a COVID-19 vaccine prior to enrollment Follow-up duration (months): 8
Vaccines:	2 doses of BNT162b2 or mRNA-1273 or Ad26.COV2.S
Variant description :
Variant description :	Variant name: Delta Evidence: Indirect evidence (prevalence of variant in the population: ≥50%)
Documents available	Protocol Yes. In English Statistical plan Yes Data-sharing stated: NR Data accessibility: NR
General comment	Some concerns over the possibility of uncontrolled confounding given the observational nature of the data and the fact that some confounders were self-reported, and uncertainty in whether those who were eligible but either refused to participate or withdrew/were lost to follow up might have differed with respect to the outcome compared to those included in the analysis.