RCT protocols
Title | NCT | Journal | Authors | Link |
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The COVIRL-001 Trial: A multicentre, prospective, randomised trial comparing standard of care (SOC) alone, SOC plus hydroxychloroquine monotherapy or SOC plus a combination of hydroxychloroquine and azithromycin in the treatment of non- critical, SARS-CoV-2 PCR-positive population not requiring immediate resuscitation or ventilation but who have evidence of clinical decline: A structured summary of a study protocol for a randomised controlled trial. | EudraCT: No. 2020-001265-36 | Trials | Feeney E | Link |
ChemoPROphyLaxIs with hydroxychloroquine For covId-19 infeCtious disease (PROLIFIC) to prevent covid-19 infection in frontline healthcare workers: A structured summary of a study protocol for a randomised controlled trial. | EudraCT: 2020-001331-26 | Trials | McEniery, C | Link |
Hydroxychloroquine efficacy and safety in preventing SARS-CoV-2 infection and COVID-19 disease severity during pregnancy (COVID-Preg): a structured summary of a study protocol for a randomised placebo controlled trial. | NCT04410562 EudraCT: 2020-001587-29 | Trials | Gonzalez, R | Link |
Comparison of two methods to clear the airways of critically ill children and adults with COVID-19 infection: a structured summary of a study protocol for a pilot randomized controlled trial. | NCT04361435 | Trials | Kawaguchi, Atsushi and Bernier, Gabrielle and Lacroix, Jacques and El Salti, Saly and Cheng, Matthew P and Lee, Todd C and Khwaja, Kosar and Jouvet, Philippe | Link |
The curative effects of shortwave diathermy on treating Novel coronavirus (COVID-19) pneumonia: A structured summary of a study protocol for a randomised controlled trial. | ChiCTR2000029972 | Trials | Nasb, Mohammad and Sayed Shah, Zulfiqar Ali and Huang, Liangjiang and Li, Qian and Chen, Hong | Link |
Impact of vitamins A, B, C, D, and E supplementation on improvement and mortality rate in ICU patients with coronavirus-19: a structured summary of a study protocol for a randomized controlled trial. | IRCT20200319046819N1 | Trials | Beigmohammadi, Mohammad Taghi; Bitarafan, Sama; Hoseindokht, Azin; Abdollahi, Alireza; Amoozadeh, Laya; Mahmoodi Ali Abadi, Maedeh; Foroumandi, Morteza; | Link |
Test and treat COVID 65 plus - Hydroxychloroquine versus placebo in early ambulatory diagnosis and treatment of older patients with COVID19: A structured summary of a study protocol for a randomised controlled trial. | NCT04351516 EudraCT: 2020-001482-37 | Trials | Göpel, Siri and Bethge, Wolfgang and Martus, Peter and Kreth, Florian and Iftner, Thomas and Joos, Stefanie and Döbele, Stefanie and Mordmüller, Benjamin and Kremsner, Peter and Ettrich, Thomas and Seufferlein, Thomas and Bitzer, Michael and Malek, Nisar | Link |
Intravenous high-dose vitamin C for the treatment of severe COVID-19: study protocol for a multicentre randomised controlled trial. | NCT04264533 | BMJ open | Liu, Fang and Zhu, Yuan and Zhang, Jing and Li, Yiming and Peng, Zhiyong | Link |
Azithromycin added to hydroxychloroquine for patients admitted to intensive care due to coronavirus disease 2019 (COVID-19)-protocol of randomised controlled trial AZIQUINE-ICU. | NCT04339816 EudraCT: 2020-001456-18 | Trials | DuÅ¡ka, FrantiÅ¡ek and Waldauf, Petr and HalaÄová, Milada and ZvonÃÄek, Václav and Bala, Jakub and BalÃk, Martin and BeneÅ¡, Jan and Klementová, Olga and Kozáková, Irena and Kubricht, Viktor and Le Roy, Anne and Vymazal, Tomáš and ÅehoÅová, Veronika and Äerný, VladimÃr and Czech Anaesthesia Clinical Trials and Audit Network, [Collective Name] | Link |
Repurposed immunomodulatory drugs for Covid-19 in pre-ICu patients - mulTi-Arm Therapeutic study in pre-ICu patients admitted with Covid-19 - Repurposed Drugs (TACTIC-R): A structured summary of a study protocol for a randomised controlled trial. | NCT04390464 EudraCT: 2020-001354-22 | Trials | Kulkarni, Spoorthy and Fisk, Marie and Kostapanos, Michalis and Banham-Hall, Edward and Bond, Simon and Hernan-Sancho, Elena and Norton, Sam and Cheriyan, Joseph and Cope, Andrew and Galloway, James and Hall, Frances and Jayne, David and Wilkinson, Ian B | Link |
Efficacy of chloroquine versus lopinavir/ritonavir in mild/general COVID-19 infection: a prospective, open-label, multicenter, randomized controlled clinical study. | ChiCTR2000029741 | Trials | Liu, Xi and Chen, Huili and Shang, Yuqi and Zhu, Hongqiong and Chen, Gongqi and Chen, Yuanli and Liu, Shaoxuan and Zhou, Yaoyong and Huang, Mingxing and Hong, Zhongsi and Xia, Jinyu | Link |
Outpatient treatment of COVID-19 with steroids in the phase of mild pneumonia without the need for admission as an opportunity to modify the course of the disease: A structured summary of a randomised controlled trial. | EudraCT: 2020-001622-64 | Trials | Saiz-RodrÃguez, Miriam and Peña, Teresa and Lázaro, Lourdes and González, Ãngel and MartÃnez, Andrés and Cordero, José A and Vicente, Juan T and Richard, Fernando and Coma, MarÃa Jesús and de Frutos, MartÃn and Labrador, Jorge and Pueyo, Ana | Link |
Protocol for a multicentre randomized controlled trial of normobaric versus hyperbaric oxygen therapy for hypoxemic COVID-19 patients | * | Boet, S. | Link | |
The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial. | Australian New Zealand Clinical Trials Registry(ACTRN12620000445976 ) | Trials | Denholm, Justin T and Davis, Joshua and Paterson, David and Roberts, Jason and Morpeth, Susan and Snelling, Thomas and Zentner, Dominica and Rees, Megan and O'Sullivan, Matthew and Price, David and Bowen, Asha and Tong, Steven Y C and ASCOT Investigator Group, [Collective Name] | Link |
Protecting Frontline Health Care Workers from COVID-19 with Hydroxychloroquine Pre-exposure Prophylaxis: A structured summary of a study protocol for a randomised placebo-controlled multisite trial in Toronto, Canada. | ISRCTN14326006 | Trials | Wright, Julie K and Tan, Darrell H S and Walmsley, Sharon L and Hulme, Jennifer and O'Connor, Erin and Snider, Carolyn and Cheng, Ivy and Chan, Adrienne K and Borgundvaag, Bjug and McLeod, Shelley and Gollob, Michael H and Clarke, Rosemarie J and Dresser, Linda and Haji, Fatima and Mazzulli, Tony and Mubareka, Samira and Jüni, Peter and Lee, Dominic and Tomlinson, George and Kain, Kevin C and Landes, Megan | Link |
A Phase 3 Open-label, Randomized, Controlled Study to Evaluate the Efficacy and Safety of Intravenously Administered Ravulizumab Compared with Best Supportive Care in Patients with COVID-19 Severe Pneumonia, Acute Lung Injury, or Acute Respiratory Distress Syndrome: A structured summary of a study protocol for a randomised controlled trial. | NCT04369469 | Trials | Smith, Keisha and Pace, Amy and Ortiz, Stephan and Kazani, Shamsah and Rottinghaus, Scott | Link |
Hydroxychloroquine for Early Treatment of Adults with Mild Covid-19: A Randomized-Controlled Trial. | * | Clinical infectious diseases : an official publication of the I | Mitjà , Oriol and Corbacho-Monné, Marc and Ubals, Maria and Tebe, Cristian and Peñafiel, Judith and Tobias, Aurelio and Ballana, Ester and Alemany, Andrea and Riera-MartÃ, Núria and Pérez, Carla A and Suñer, Clara and Laporte, Pep and Admella, Pol and Mitjà , Jordi and Clua, Mireia and Bertran, Laia and Sarquella, Maria and Gavilán, Sergi and Ara, Jordi and Argimon, Josep M and Casabona, Jordi and Cuatrecasas, Gabriel and Cañadas, Paz and Elizalde-Torrent, Aleix and Fabregat, Robert and Farré, Magà and Forcada, Anna and Flores-Mateo, Gemma and Muntada, Esteve and Nadal, Núria and Narejos, Silvia and Gil-Ortega, Aroa N and Prat, Nuria and Puig, Jordi and Quiñones, Carles and Reyes-Ureña, Juliana and RamÃrez-Viaplana, Ferran and Ruiz, Lidia and Riveira-Muñoz, Eva and Sierra, Alba and Velasco, César and Vivanco-Hidalgo, Rosa Maria and SentÃs, Alexis and G-Beiras, Camila and Clotet, Bonaventura and Vall-Mayans, Martà and BCN PEP-CoV-2 RESEARCH GROUP, [Collective Name] | Link |
Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19: A Randomized Trial. | NCT04308668 | Annals of internal medicine | Skipper, Caleb P and Pastick, Katelyn A and Engen, Nicole W and Bangdiwala, Ananta S and Abassi, Mahsa and Lofgren, Sarah M and Williams, Darlisha A and Okafor, Elizabeth C and Pullen, Matthew F and Nicol, Melanie R and Nascene, Alanna A and Hullsiek, Kathy H and Cheng, Matthew P and Luke, Darlette and Lother, Sylvain A and MacKenzie, Lauren J and Drobot, Glen and Kelly, Lauren E and Schwartz, Ilan S and Zarychanski, Ryan and McDonald, Emily G and Lee, Todd C and Rajasingham, Radha and Boulware, David R | Link |
Antiviral Activity and Safety of Darunavir/Cobicistat for the Treatment of COVID-19. | NCT04252274 | Open forum infectious diseases | Chen, Jun and Xia, Lu and Liu, Li and Xu, Qingnian and Ling, Yun and Huang, Dan and Huang, Wei and Song, Shuli and Xu, Shuibao and Shen, Yingzhong and Lu, Hongzhou | Link |
Randomized Controlled Study Evaluating Efficiency of Low Intensity Transcranial Direct Current Stimulation (tDCS) for Dyspnea Relief in Mechanically Ventilated COVID-19 Patients in ICU: The tDCS-DYSP-COVID Protocol. | NCT03640455 | Frontiers in medicine | Azabou, Eric and Bao, Guillaume and Heming, Nicholas and Bounab, Rania and Moine, Pierre and Chevallier, Sylvain and Chevret, Sylvie and Resche-Rigon, Matthieu and Siami, Shidaps and Sharshar, Tarek and Lofaso, Frederic and Annane, Djillali | Link |
Hydroxychloroquine in Outpatient Adults With COVID-19 | NCT04333654 | Link | ||
Pre-exposure prophylaxis with hydroxychloroquine for high-risk healthcare workers during the COVID-19 pandemic: A structured summary of a study protocol for a multicentre, double-blind randomized controlled trial. | NCT04331834 | Trials | Grau-Pujol B; Camprubí D; Marti-Soler H; Fernández-Pardos M; Guinovart C; Muñoz J; | Link |
RECOVERY- Respiratory Support: Respiratory Strategies for patients with suspected or proven COVID-19 respiratory failure; Continuous Positive Airway Pressure, High-flow Nasal Oxygen, and standard care: A structured summary of a study protocol for a randomised controlled trial. | ISRCTN16912075 | Trials | Perkins GD; Couper K; Connolly B; Baillie JK; Bradley JM; Dark P; De Soyza A; Gorman E; Gray A; Hamilton L; Hart N; Ji C; Lall R; McGowan N; Regan S; Simonds AK; Skilton E; Stallard N; Stimpson E; Yeung J; McAuley DF; | Link |
An open label cluster randomized controlled trial of chloroquine, hydroxychloroquine or only supportive care in patients admitted with moderate to severe COVID-19 (ARCHAIC) - Protocol publication | * | European journal of clinical investigation | Weehuizen JM | Link |
Evaluation of Convalescent Plasma versus Standard of Care for the Treatment of COVID-19 in Hospitalazed Patients: study protocol for a phase 2 randomized, open-label, controlled, multicenter trial | NCT04345523 | medRxiv | Diago-Sempere, E. | Link |
A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the intensive care unit (MelCOVID study): a structured summary of a study protocol for a randomized controlled trial. | EudraCT:2020-001808-42 | Trials | Rodríguez-Rubio M; Figueira JC; Acuña-Castroviejo D; Borobia AM; Escames G; de la Oliva P; | Link |
Nigella sativa supplementation to treat symptomatic mild COVID-19: A structured summary of a protocol for a randomised, controlled, clinical trial. | NCT04401202 | Trials | Koshak AE; Koshak EA; Mobeireek AF; Badawi MA; Wali SO; Malibary HM; Atwah AF; Alhamdan MM; Almalki RA; Madani TA; | Link |
Pakistan Randomized and Observational Trial to Evaluate Coronavirus Treatment (PROTECT) of Hydroxychloroquine, Oseltamivir and Azithromycin to treat newly diagnosed patients with COVID-19 infection who have no comorbidities like diabetes mellitus: A structured summary of a study protocol for a randomized controlled trial. | NCT04338698 | Trials | Akram J; Azhar S; Shahzad M; Latif W; Khan KS; | Link |
Evaluation of the efficacy and safety of intravenous remdesivir in adult patients with severe COVID-19: study protocol for a phase 3 randomized, double-blind, placebo-controlled, multicentre trial. | NCT 04257656 | Trials | Wang Y | Link |
Efficacy of Liu-zi-jue in Patients with 2019 Novel Coronavirus Pneumonia (COVID-19): structured summary of a study protocol for a randomized controlled trial. | ChiCTR2000032367 | Trials | Zhang S | Link |
Hydroxychloroquine vs. Azithromycin for Hospitalized Patients with Suspected or Confirmed COVID-19 (HAHPS): Protocol for a Pragmatic, Open Label, Active Comparator Trial. | NCT04329832 | Annals of the American Thoracic Society | Brown S | Link |
An online solution focused brief therapy for adolescent anxiety during the novel coronavirus disease (COVID-19) pandemic: a structured summary of a study protocol for a randomised controlled trial. | ChiCTR2000030989 | Trials | Chen S | Link |
Post-exposure prophylaxis or pre-emptive therapy for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): study protocol for a pragmatic randomized-controlled trial. | NCT04308668 | Canadian journal of anaesthesia | Lother S | Link |
Effectiveness of glucocorticoid therapy in patients with severe coronavirus disease 2019: protocol of a randomized controlled trial. | ChiCTR2000029386 | Chinese medical journal | Qin Y | Link |
Hydroxychloroquine alone or in combination with azithromycin to prevent major clinical events in hospitalised patients with coronavirus infection (COVID-19): rationale and design of a randomised, controlled clinical trial | NCT04322123 | medrxiv | Cavalcanti AB | Link |
A Proposed Randomized, Double Blind, Placebo Controlled Study Evaluating Doxycycline for the Prevention of COVID-19 Infection and Disease In Healthcare Workers with Ongoing High Risk Exposure to COVID-19 | * | medrxiv | Yates PA | Link |
Plasma from donors recovered from the new Coronavirus 2019 as therapy for critical patients with COVID-19 (COVID-19 plasma study): a multicentre study protocol. | NCT04321421 | Internal and emergency medicine | Perotti C | Link |
An open label cluster randomized controlled trial of chloroquine, hydroxychloroquine or only supportive care in patients admitted with moderate to severe COVID-19 (ARCHAIC) - Protocol publication | * | European journal of clinical investigation | Weehuizen JM | Link |
Rationale and Design of ORCHID: A Randomized Placebo-Controlled Trial of Hydroxychloroquine for Adults Hospitalized with COVID-19. | NCT04332991 | Annals of the American Thoracic Society | Casey J | Link |
A prospective, randomised, double blind placebo-controlled trial to evaluate the efficacy and safety of tocilizumab in patients with severe COVID-19 pneumonia (TOC-COVID): A structured summary of a study protocol for a randomised controlled trial. | EudraCT: No. 2020-001408-41 | Trials | Rilinger J | Link |
Controlled, double-blind, randomized trial to assess the efficacy and safety of hydroxychloroquine chemoprophylaxis in SARS CoV2 infection in healthcare personnel in the hospital setting: A structured summary of a study protocol for a randomised controlled trial. | Eudra CT: No. 2020-001704-42 | Trials | Cuadrado-Lavan A | Link |
Efficacy of hydroxychloroquine for post-exposure prophylaxis to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among adults exposed to coronavirus disease (COVID-19): a structured summary of a study protocol for a randomised controlled trial. | NCT04328961 | Trials | Barnabas RV | Link |
A randomized multicenter clinical trial to evaluate the efficacy of melatonin in the prophylaxis of SARS-CoV-2 infection in high-risk contacts (MeCOVID Trial): A structured summary of a study protocol for a randomised controlled trial. | EudraCT: No. 2020-001530-35 | Trials | Garcia I | Link |
Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): A structured summary of a study protocol for a randomised, controlled trial. | NCT03042143 | Trials | Gorman E | Link |
Effectiveness of Interferon Beta 1a, compared to Interferon Beta 1b and the usual therapeutic regimen to treat adults with moderate to severe COVID-19: structured summary of a study protocol for a randomized controlled trial. | NCT04343768 | Trials | Irvani S | Link |
A short, animated video to improve good COVID-19 hygiene practices: a structured summary of a study protocol for a randomized controlled trial. | German CT Register :DRKS00021582 | Trials | Vandormael A | Link |
Umbilical cord blood therapy to prevent progression of COVID-19 related pneumonia: a structured summary of a study protocol for a pilot randomised controlled trial. | ACTRN12620000478910 | Trials | Malhotra A | Link |
Effect of hydroxychloroquine on prevention of COVID-19 virus infection among healthcare professionals: a structured summary of a study protocol for a randomised controlled trial. | IRCT20120826010664N6 | Trials | Pirjani R | Link |
Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID): A structured summary of a study protocol for a randomised controlled trial. | NCT04330638 | Trials | Maes | Link |
Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial. | NCT04326920 | Trials | Bosteels B | Link |
Norwegian Coronavirus Disease 2019 (NO COVID-19) Pragmatic Open label Study to assess early use of hydroxychloroquine sulphate in moderately severe hospitalised patients with coronavirus disease 2019: A structured summary of a study protocol for a randomised controlled trial. | NCT04316377 | Trials | Lyngbakken M | Link |
The Mechanism and Clinical Outcome of patients with Corona Virus Disease 2019 Whose Nucleic Acid Test has changed from negative to positive, and the therapeutic efficacy of Favipiravir: A structured summary of a study protocol for a randomised controlled trial. | NCT04333589 | Trials | Li J | Link |
Adding Colchicine to the Antiretroviral Medication - Lopinavir/Ritonavir (Kaletra) in Hospitalized Patients with Non-Severe Covid-19 Pneumonia: A Structured Summary of a Study Protocol for a Randomized Controlled Trial. | NCT04360980 | Trials | Dalili N | Link |
Two Randomized Controlled Trials of Bacillus Calmette-Guérin Vaccination to reduce absenteeism among health care workers and hospital admission by elderly persons during the COVID-19 pandemic: A structured summary of the study protocols for two randomised controlled trials. | NCT04328441 | Trials | Ten Doesschate T | Link |
Rationale and design of the PRAETORIAN-COVID trial: A double-blind, placebo-controlled randomized clinical trial with valsartan for PRevention of Acute rEspiraTORy dIstress syndrome in hospitAlized patieNts with SARS-COV-2 Infection Disease. | NCT04335786 | American heart journal | Gommans DH | Link |
Protocol for a randomized controlled trial testing inhaled nitric oxide therapy in spontaneously breathing patients with COVID-19. | * | medRxiv | Berra, L. | Link |
Evaluating the efficacy and safety of human anti-SARS-CoV-2 convalescent plasma in severely ill adults with COVID-19: A structured summary of a study protocol for a randomized controlled trial. | NCT04359810 | Trials | Eckhardt C | Link |
Efficacy and safety of Anluohuaxian in the treatment of patients with severe Coronavirus disease 2019- a multicenter, open label, randomized controlled study: a structured summary of a study protocol for a randomised controlled trial. | NCT04334265 | Trials | Zhang C | Link |
A pilot study of therapeutic plasma exchange for serious SARS CoV-2 disease (COVID-19): A structured summary of a randomized controlled trial study protocol. | ISRCTN21363594 | Trials | Faqihi F | Link |
The SARS-CoV-2 Ivermectin Navarra-ISGlobal Trial (SAINT) to Evaluate the Potential of Ivermectin to Reduce COVID-19 Transmission in low risk, non-severe COVID-19 patients in the first 48 hours after symptoms onset: A structured summary of a study protocol for a randomized control pilot trial. | EudraCT: No. 2020-001474-29 | Trials | Chaccour C | Link |
Treatment with Hydroxychloroquine vs Hydroxychloroquine + Nitazoxanide in COVID-19 patients with risk factors for poor prognosis: A structured summary of a study protocol for a randomised controlled trial. | NCT04341493 | Trials | Calderon J | Link |
Proactive Prophylaxis With Azithromycin and HydroxyChloroquine in Hospitalised Patients With COVID-19 (ProPAC-COVID): A structured summary of a study protocol for a randomised controlled trial. | NCT04322396 | Trials | Sivapalan, P | Link |
An internet-based intervention to face stress during social isolation with guided relaxation and meditation: protocol for a randomized controlled study. | PRR1-10.2196/19236 | JMIR research protocols | Pizzoli, | Link |
Safety and efficacy assessment of allogeneic human dental pulp stem cells to treat patients with severe COVID-19: structured summary of a study protocol for a randomized controlled trial (Phase I / II). | NCT04336254 | Trials | Ye, Q | Link |
A description of Covid-19 modifications to the TEAMS study protocol for remotely delivering teleassessment/teletraining of complementary alternative medicine among people with multiple sclerosis: protocol for a randomized controlled effectiveness trial. | NCT03117881 | JMIR research protocols | Lai, B | Link |
Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial. | NCT04355364 | Trials | Desilles, J P | Link |
Letter to the editor: efficacy of different methods of combination regimen administrations including dexamethasone, intravenous immunoglobulin, and interferon-beta to treat critically ill COVID-19 patients: a structured summary of a study protocol for a randomized controlled trial. | IRCT20120225009124N4 | Trials | Abdolahi, N | Link |
AGILE-ACCORD: A Randomized, Multicentre, Seamless, Adaptive Phase I/II Platform Study to Determine the Optimal Dose, Safety and Efficacy of Multiple Candidate Agents for the Treatment of COVID-19: A structured summary of a study protocol for a randomised platform trial. | EudraCT: No. 2020-001860-27 | Trials | Griffiths, G | Link |
Triiodothyronine for the treatment of critically ill patients with COVID-19 infection: A structured summary of a study protocol for a randomised controlled trial. | NCT04348513 | Trials | Pantos, C | Link |
A prospective, randomized, controlled study assessing vagus nerve stimulation using the gammaCore®-Sapphire device for patients with moderate to severe CoViD-19 Respiratory Symptoms (SAVIOR): A structured summary of a study protocol for a randomised controlled trial". | NCT04368156 | Trials | Tornero, C | Link |
Randomised controlled trial comparing efficacy and safety of high versus low Low-Molecular Weight Heparin dosages in hospitalized patients with severe COVID-19 pneumonia and coagulopathy not requiring invasive mechanical ventilation (COVID-19 HD): a structured summary of a study protocol. | EudraCT: No. 2020-001972-13 | Trials | Marietta, M | Link |
Therapeutic pulmonary telerehabilitation protocol for patients affected by COVID-19, confined to their homes: study protocol for a randomized controlled trial. | Brazilian CT Registry RBR-6m69fc | Trials | Gonzalez-Gerez, J J | Link |
COVID-19-associated ARDS treated with DEXamethasone (CoDEX): Study design and rationale for a randomized trial. | NCT04327401 | medRxiv | Tomazini, B. M. | Link |
Protocol of a randomized controlled trial testing inhaled Nitric Oxide in mechanically ventilated patients with severe acute respiratory syndrome in COVID-19 (SARS-CoV-2). | NCT04306393 | medRxiv | Lei, C. | Link |
Recommendations on Core Outcome Sets for clinical trials or clinical research are being developed by the COMET Initiative.