Trial *
Publication Albani F, medRxiv, 2020
Dates: 2020-02-20 to 2020-05-10
| Methods | |
| Non-randomized study | |
| Location :
Single center / Italy Follow-up duration (days): 84 | |
| Inclusion criteria | Clinical, demographic and laboratory data from all adult patients who were admitted to the hospital and had a positive test for SARS-CoV2 from biological material were recorded at admission. Tests were conducted with Real Time Polymerase-Chain-Reaction assay (RT-PCR) |
| Exclusion criteria | Patients younger than 18 years or with no available outcome at the time of analysis were excluded from the study |
| Type of analysis | Propensity score stratification/adjustment |
| Interventions | |
| Treatment
Corticosteroid (*) Duration : median 6 (IQR 4-10) days in su |
|
| Control
Standard care Definition of Standard care: Not reported | |
| Participants | |
| N analyzed 1443 participants (n1=559 / n2= 884) | |
| Characteristics of participants N=1403 Mean age : NR 924 males Severity : Mild: n=* / Moderate: n=*/ Severe: n=* Critical: n=* | |
| Primary outcome | |
| In the register In-hospital mortality was the primary outcome | |
| In the report In-hospital mortality was the primary outcome | |
| Documents avalaible |
Protocol NR Statistical plan NR Data-sharing stated Yes |
| Risk of bias Overall The overall risk of bias reported in the table corresponds to the highest risk of bias for the outcomes assessed for the systematic review |
Serious |
| Notes | A retrospective analysis of prospectively collected data was carried out. Propensity score with overlap method was used to balance some covariate across the two study cohorts. Table 1 shows that not all relevant variables were balanced. No registration or protocol were available. |