Trial NCT02735707, NCT04505774, NCT04359277, NCT04372589
Publication Lawler PR, medRxiv, 2021
Primary outcome on the report: Organ support-free days, an ordinal outcome composed of survival to hospital discharge and, among survivors, the number of days free of ICU-level organ support through day 21. Any death during the index hospitalization through 90 days was assigned –1.

Note: The risk of bias by domain corresponds to the highest risk of bias among outcomes by domain.
The overall risk of bias corresponds to the overall highest risk of bias assessed among outcomes.