Trial *
Publication Dengiz E, Med Gas Res (2021) (published paper)
Dates: 2020-08-01 to 2020-09-30
Funding: Private (Edis Pharma Pharmaceutical İndustry)
Conflict of interest: Yes
Methods | |
RCT | |
Location :
Single center / Turkey Follow-up duration (days): 5 | |
Inclusion criteria |
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Exclusion criteria |
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Interventions | |
Treatment
Oxygen-Ozone 0.2 parts per million/second ozone gas passed through olive oil applied 3 times a day for 10 minutes at intervals of 5 minutes for 5 days |
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Control
Standard care | |
Participants | |
Randomized participants : Oxygen-Ozone=15 Standard care=15 | |
Characteristics of participants N= 30 Mean age : NR 17 males Severity : Mild: n=* / Moderate: n=* / Severe: n=* Critical: n=* Number of vaccinated participants: NR | |
Primary outcome | |
In the register NR | |
In the report NR | |
Documents available |
Protocol NR Statistical plan NR Data-sharing willing stated in the publication: Yes |
Risk of bias Overall The overall risk of bias reported in the table corresponds to the highest risk of bias for the outcomes assessed for the systematic review |
Some concerns |
General comment | Only the published article was used in data extraction and risk of bias assessment. No protocol or study registry were available. There was no information on randomization process, sample size calculations or if outcomes were determined a priori. |