Trial *
Publication Rashad A, 2021 (preprint)
Funding: Not reported/unclear
Conflict of interest: No
| Methods | |
| RCT | |
| Location :
Single center / Egypt Follow-up duration (days): 15 | |
| Inclusion criteria | mild COVID-19 according to WHO classification;
Oxygen saturation > 90% on room air; Imaging shows less than 25% infiltrates on CT chest |
| Exclusion criteria | NR |
| Interventions | |
| Treatment 1 Azithromycin | |
| Control Standard care | |
| Control Clarithromycin | |
| Participants | |
| Randomized 305 participants n1=107/ n2=99/ n3=99 | |
| Characteristics of participants N=305 Mean age : 44.4 214 males Severity : Mild: n=0 / Moderate: n=0/ Severe: n=0 Critical: n=0 | |
| Primary outcome | |
| In the register NR | |
| In the report NR | |
| Documents available |
Protocol NR Statistical plan NR Data-sharing stated NR |
| Risk of bias Overall The overall risk of bias reported in the table corresponds to the highest risk of bias for the outcomes assessed for the systematic review |
* |
| General comment |
This study is pending contact with authors. No review-specific outcomes reported/extracted.
The pre-print article was used in data extraction and risk of bias assessment. No trial registry, protocol or statistical analysis plan was available. Consequently, there was no information on whether the trial was conducted and analyzed as planned. The authors reported no details on randomization procedure or blinding, and there was a large proportion of missing outcome data. The primary outcome, exclusion criteria and the proportion of participants randomized per arm were not reported. No outcome data were reported in a manner that allowed for extraction. |