Pharmacologic treatments for covid-19 patients

Nitazoxanide vs Placebo

This comparison will not be updated. Last search date 28 Feb, 2022.


Outpatients

Forest plots
(last update: 2022-04-29)

Summary of findings
(last update: 2021-06-03)

Hospitalized patients

Forest plots
(last update: 2022-01-04)

Summary of findings
(last update: 2022-03-30)

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Permanent URL for this comparison: https://covid-nma.com/living_data/index.php?comparison=118

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Trial Funding Comparisons Design Participants Sample size Overall risk
of bias
Highest assessment
Full description
Treatment 1 Treatment 2
NCT04486313
Rossignol JF, EClinicalMedicine, 2022
Full text
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Commentary
Commentary
Commentary
Private

Nitazoxanide

Placebo

RCT Outpatients with confirmed or suspected COVID-19 (mild, symptomatic) treated at 36 centers in Puerto Rico and USA. N=379
Some concerns
Details

Full description

NCT04463264
Silva M, medRxiv, 2021
Full text
Commentary
Commentary
Private

Nitazoxanide

Placebo

RCT Outpatients and inpatients with confirmed COVID-19 (asymptomatic or symptomatic-mild) treated by or admitted to two centers in Argentina N=46
High
Details

Full description

NCT04348409
Blum VF, EClinicalMedicine, 2021
Full text
Full text
Commentary
Private

Nitazoxanide

Placebo

RCT Patients with confirmed COVID-19 (mild/moderate) admitted to 6 centers in Brazil. N=50
Some concerns
Details

Full description

NCT04552483
Rocco PRM, Eur Respir J, 2020
Full text
Commentary
Mixed

Nitazoxanide

Placebo

RCT Outpatients with confirmed COVID-19 (mild) treated at 7 centers in Brazil N=475
Some concerns
Details

Full description