Convalescent plasma vs Standard care/Placebo (RCT)

Hospitalized patients

FOREST PLOTS -2022-08-04

Studies description

Trial CTRI/2020/04/024775
Publication PLACID - Agarwal A, BMJ (2020) (published paper)
Dates: 2020-04-22 to 2020-07-14
Funding: Public/non profit (Indian Council of Medical Research (ICMR))
Conflict of interest: No

Trial NCT04356534
Publication AlQahtani M, Sci Rep (2021) (published paper)
Dates: 2020-04-19 to 2020-06-15
Funding: Public/non profit (Ministry of Health Bahrain and the College of Surgeons in Ireland-Bahrain)
Conflict of interest: No

Trial NCT04345523
Publication ConPlas-19 - Avendano-Sola C, J Clin Invest (2021) (published paper)
Dates: 2020-04-04 to 2021-02-05
Funding: Public/non profit (Government of Spain, Instituto de Salud Carlos III)
Conflict of interest: No

Trial NCT04425915
Publication COPLA-II trial - Bajpai M, BMJ Open (2022) (published paper)
Dates: 2020-06-14 to 2020-11-17
Funding: No specific funding (The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors. )
Conflict of interest: No

Trial ISRCTN85216856
Publication Baldeon ME, Transfus Med (2022) (published paper)
Dates: 2020-05-10 to 2020-10-31
Funding: Public/non profit (Salvar Vidas Ecuador (SalvarVidasEC))
Conflict of interest: No

Trial NCT04397757
Publication PennCCP2 - Bar KJ, J Clin Invest (2021) (published paper)
Dates: 2020-05-18 to 2021-01-08
Funding: Public/non profit (University of Pennsylvania. There was no commercial support for this trial.)
Conflict of interest: Yes

Trial NCT04803370
Publication Bargay-Lleonart J, J Clin Med (2022) (published paper)

Funding: Public/non profit (Health Research Institute of the Balearic Islands)
Conflict of interest: No

Trial NCT04348656
Publication CONCOR-1 - Begin P, medRxiv (2021) (preprint)
Dates: 2020-05-14 to 2021-01-29
Funding: Public/non profit (Canadian Institutes of Health Research; Ontario COVID-19 Rapid Research Fund; Toronto COVID-19 Action Initiative 2020 (University of Toronto); University Health Network Emergent Access Innovation Fund; University Health Academic Health Science Centre Alternative Funding Plan (Sunnybrook Health Sciences Centre); Ministère de l'Économie et de l'Innovation (Québec); Fond de Recherche du Québec en Santé; Saskatchewan Ministry of Health; University of Alberta Hospital Foundation; Alberta Health Services COVID-19 Foundation Competition; Sunnybrook Health Sciences Centre Foundation; Fondations CHU Ste-Justine; The Ottawa Hospital Academic Medical Organization; The Ottawa Hospital Foundation COVID-19 Research Fund; Fondation du CHUM; Sinai Health System Foundation and McMaster University. These did not have any role in the writing of the manuscript or the decision to submit it for publication. The authors did not receive payments from any pharmaceutical company or other agency to write this article.)
Conflict of interest: No

Trial RBR-7f4mt9f
Publication De Santis GC, Emerg Infect Dis (2022) (published paper)
Dates: 2020-04-14 to 2020-11-30
Funding: Public/non profit (Fundação de Amparo à Pesquisa do Estado de São Paulo)
Conflict of interest: *

Trial NCT02735707
Publication REMAP-CAP - Estcourt L, JAMA (2021) (published paper)
Dates: 2020-05-05 to 2021-01-18
Funding: Mixed (PREPARE consortium by the European Union; Australian National Health and Medical Research Council; Australian Medical Research Future Fund; New Zealand Health Research Council; Canadian Institutes of Health Research COVID-19 Rapid Research Funding; Canadian Institute of Health Research Strategy for Patient-Oriented Research Innovative Clinical Trials Program Grant; NIHR; UK NIHR; NIHR Imperial Biomedical Research Centre; Health Research Board of Ireland; UPMC Learning While Doing Program; Translational Breast Cancer Research Consortium; Pittsburgh Foundation; French Ministry of Health; Minderoo Foundation; Wellcome Trust Innovations Project; Australian government; DHSC; EU SoHo Grants)
Conflict of interest: Yes

Trial NCT04405310
Publication Fernandez-Sanchez V, Research Square (2022) (preprint)
Dates: 2020-05-20 to 2020-10-10
Funding: Public/non profit (CEMEVAV (Centro Medico Naval, Naval Medical Center))
Conflict of interest: No

Trial NCT04342182
Publication Gharbharan A, Nat Commun (2021) (published paper)
Dates: 2020-04-08 to 2020-06-14
Funding: Mixed (The Erasmusfoundation, Ypsilo and Health Holland)
Conflict of interest: No

Trial NCT04600440
Publication Holm K, BMC Res Notes (2021) (published paper)
Dates: 2020-06-01 to 2021-01-30
Funding: Public/non profit (Skåne Region)
Conflict of interest: No

Trial NCT04381936; EudraCT 2020-001113-21; ISRCTN5018967
Publication RECOVERY-CP - Horby P, Lancet (2021) (published paper)
Dates: 2020-05-28 to 2021-01-15
Funding: Public/non profit (UK Research and Innovation (Medical Research Council) and National Institute of Health Research )
Conflict of interest: No

Trial NCT04542941
Publication Kirenga B, BMJ Open Respir Res (2021) (published paper)
Dates: 2020-09-23 to 2020-12-02
Funding: Public/non profit (Government of Uganda through the Makerere University Research and Innovations Fund)
Conflict of interest: No

Trial NCT04433910; EudraCT 2020-001310-38
Publication CAPSID - Koerper S, J Clin Invest (2021) (published paper)
Dates: 2020-08-30 to 2020-12-24
Funding: Public/non profit (Bundesministerium fuer Gesundheit (German Federal Ministry of Health))
Conflict of interest: Yes

Trial ChiCTR2000029757
Publication Li L, JAMA (2020) (published paper)
Dates: 2020-02-14 to 2020-04-01
Funding: Public/non profit (Chinese Academy of Medical Sciences InnovationFund for Medical Sciences (CIFMS) grants2020-I2M-CoV19-006, 2016-I2M-3-024 (Dr Z. Liu),and 2017-I2M-1-009 (Dr L. Li) and the NonprofitCentral Research Institute Fund of ChineseAcademy of Medical Scie)
Conflict of interest: Yes

Trial NCT04479163
Publication Libster R, N Engl J Med (2021) (published paper)
Dates: 2020-06-04 to 2020-10-25
Funding: Mixed (The Bill & Melinda Gates Foundation; The Fundacion INFANT Pandemic Fund)
Conflict of interest: Yes

Trial NCT04716556
Publication TSUNAMI - Menichetti F , JAMA (2021) (published paper)
Dates: 2020-07-15 to 2020-12-08
Funding: Public/non profit (Italian National Institute of Health, Istituto Superiore di Sanità (ISS) and the Italian Medicines Agency, Agenzia Italiana del Farmaco (AIFA).)
Conflict of interest: No

Trial NCT04364737
Publication CONTAIN COVID-19 - Ortigoza MB, JAMA Intern Med (2021) (published paper)
Dates: 2020-04-17 to 2021-03-15
Funding: Public/non profit (Philanthropic funds to New York University and Montefiore Medical Center/Albert Einstein College of Medicine; grant from the G. Harold and Leila Y. Mathers Foundation (Dr Pirofski); a Damon Runyon Cancer Research Foundation Physician-Scientist award (Dr Upadhyay); grants from the NCATS/NIH Centers for Translational Science Awards (CTSA); a contract with the Biomedical Advanced Research and Development Authority (BARDA) through the Department of Health and Human Services and the Operation Warp Speed interagency program; Irma and Abram S. Croll Charitable Trust; the Michael Price Foundation; Montefiore COVID-19 Emergency Fund. )
Conflict of interest: Yes

Trial IRCT20200310046736N1
Publication Pouladzadeh M, Intern Emerg Med (2021) (published paper)
Dates: 2020-03-01 to 2020-05-30
Funding: Public/non profit (Ahvaz University of Medical Sciences)
Conflict of interest: *

Trial *
Publication Rasheed A, Le Infezioni in Medi (2020) (published paper)

Funding: Public/non profit (Karkh health directorate in Baghdad; Alkharkh General Directorate of Health, Alkadymia, Baghdad )
Conflict of interest: No

Trial CTRI/2020/05/025209
Publication Ray Y, Nat Commun (2022) (published paper)
Dates: 2020-05-31 to 2020-10-12
Funding: Public/non profit (Council of Scientific Industrial Research (CSIR), Govt. of India and Fondation Botnar)
Conflict of interest: No

Trial NCT04332835
Publication Rojas M, BMC Infect Dis (2022) (published paper)
Dates: 2020-08-08 to 2020-11-13
Funding: Mixed (Universidad del Rosario, IDCBIS (Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud), ISA Group and Suramericana.)
Conflict of interest: Yes

Trial NCT04530370
Publication Salman OH, Egypt J Anaesth (2020) (published paper)
Dates: 2020-05-29 to 2020-08-30
Funding: Not reported/unclear
Conflict of interest: No

Trial NCT04547660
Publication PLACOVID - Sekine L, Eur Respir J (2021) (published paper)
Dates: 2020-07-15 to 2020-12-10
Funding: Public/non profit (Fundação de Amparo à Pesquisa do Estado de São Paulo, Instituto Cultural Floresta, Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul)
Conflict of interest: No

Trial NCT04362176
Publication PassITON - Self WH, Chest (2022) (published paper)
Dates: 2020-04-28 to 2021-06-01
Funding: Public/non profit (National Center for Advancing Translational Sciences (NCATS); the Dolly Parton COVID-19 Research Fund.)
Conflict of interest: Yes

Trial NCT04383535
Publication PlasmAr - Simonovich VA, N Engl J Med (2020) (published paper)
Dates: 2020-05-28 to 2020-08-27
Funding: Mixed (Self-supported by participant institutions; Research Council of Hospital Italiano de Buenos Aires; National Council of Scientific Research and Technology (CONICET) Institute, National Ministry of Science, Technology, a)
Conflict of interest: *

Trial NCT04415086
Publication COOP-COVID-19-MCTI - Song ATW, Lancet Reg Health Am (2022) (published paper)
Dates: 2020-06-02 to 2020-11-18
Funding: Public/non profit (Brazilian Ministry of Science, Technology and Innovation, Fundação de Amparo à Pesquisa do Estado de São Paulo.)
Conflict of interest: No

Trial NCT04516811
Publication PROTECT-Patient - van den Berg K, Sci Rep (2022) (published paper)
Dates: 2020-09-30 to 2021-01-14
Funding: Public/non profit (The ELMA South Africa Foundation; Allan & Gill Gray Philanthropy LIMITED; Wellcome; the South African Medical Research Council)
Conflict of interest: No